Somatostatin Increases Voltage-Gated K+ Currents in GH3 Cells through Activation of Multiple Somatostatin Receptors
نویسندگان
چکیده
منابع مشابه
Somatostatin Decorated Quantum Dots Nanoparticles for Targeting of Somatostatin Receptors
Due to the unique optical properties like high brightness and narrow emission bands of Quantum dots, it is used as simple fluorescence materials in bio-imaging, immunoassays, microarrays, and other applications. To easy invistigate cell lines that overexpressed somtostatin receptors, somatostatin (SST) was conjugated with Quantum dots carrying PEG amine (Qdots-PEG-NH2). The conjugation of SST t...
متن کاملSomatostatin Decorated Quantum Dots Nanoparticles for Targeting of Somatostatin Receptors
Due to the unique optical properties like high brightness and narrow emission bands of Quantum dots, it is used as simple fluorescence materials in bio-imaging, immunoassays, microarrays, and other applications. To easy invistigate cell lines that overexpressed somtostatin receptors, somatostatin (SST) was conjugated with Quantum dots carrying PEG amine (Qdots-PEG-NH2). The conjugation of SST t...
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We investigated the cellular localization in the salamander retina of one of the somatostatin [or somatotropin release-inhibiting factor (SRIF)] receptors, sst(2A), and studied the modulatory action of SRIF on voltage-gated K(+) and Ca(2+) currents in rod and cone photoreceptors. SRIF immunostaining was observed in widely spaced amacrine cells, whose perikarya are at the border of the inner nuc...
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Somatostatin is a small neuropeptide that is produced in the central nervous system, where it acts as a neurotransmitter. This neuropeptide also has an important role in the neuroendocrine system as an inhibitor of hormone release, the most striking example of which is the inhibition of growth hormone release. The role of somatostatin in eye disease recently became of interest because of its ro...
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A biophysical analysis of the voltage-gated K (Kv) currents of frog saccular hair cells enzymatically isolated with bacterial protease VIII was carried out, and their contribution to the cell electrical response was addressed by a modeling approach. Based on steady-state and kinetic properties of inactivation, two distinct Kv currents were found: a fast inactivating IA and a delayed rectifier I...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2005
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2005-0696